Oxyntomodulin
A gut hormone that reduces appetite and is being developed as a new injectable treatment for obesity.
Plain English
Patient-Friendly Explanation
Oxyntomodulin is a naturally occurring gut hormone that reduces appetite and helps control blood sugar. Scientists are developing it into an injectable medication for obesity. It works in a similar way to the GLP-1 medicines that are already widely used.
Medical
Clinical Definition
Oxyntomodulin is a peptide hormone co-secreted with GLP-1 from intestinal L-cells that acts as a dual agonist of the GLP-1 and glucagon receptors. It suppresses appetite, delays gastric emptying and increases energy expenditure through glucagon receptor agonism. Pharmaceutical analogues are under investigation for obesity, with early trials showing clinically meaningful weight loss.
Key Insight
Why It Matters
New medications that act on multiple hormone pathways are expanding the options for treating obesity. Accord Medical Clinic stays current with these advances so we can offer you the most effective, evidence-based treatments available.
Sources
Reviewed against standard medical references.
Medically reviewed by
Family Physician & Registered Acupuncturist, Accord Medical Clinic. MBBS (NUS), Graduate Diploma in Family Medicine (NUS), Graduate Diploma in Acupuncture (Singapore College of TCM).
Last reviewed: August 2026
This page is general health education, not medical advice. Whether any treatment is appropriate for you is a decision made in consultation after assessment.