Diethylpropion
A short-term prescription appetite suppressant that helps jump-start weight loss by reducing hunger signals in the brain.
Plain English
Patient-Friendly Explanation
Diethylpropion is a prescription weight loss medication that helps reduce appetite by affecting certain chemicals in the brain that control hunger. It is used for short-term treatment, usually a few weeks, alongside a doctor-supervised diet and exercise programme. This medication is typically prescribed to patients who need an initial boost in their weight loss journey before transitioning to lifestyle-based management.
Medical
Clinical Definition
Diethylpropion (also known as amfepramone) is a sympathomimetic amine anorectic agent that acts as a norepinephrine-dopamine reuptake inhibitor. It stimulates the release of norepinephrine in the hypothalamic feeding centre, suppressing appetite. It is a Schedule IV controlled substance indicated for short-term use (up to 12 weeks) as an adjunct to caloric restriction in patients with a BMI of 30 or greater, or 27 or greater with comorbidities.
Key Insight
Why It Matters
Diethylpropion is one of the most cost-effective prescription weight loss medications available in Singapore. Understanding its role, benefits, and limitations helps patients make informed decisions about pharmacological weight management under proper medical supervision at Accord Medical.
Sources
Reviewed against standard medical references.
Medically reviewed by
Family Physician & Registered Acupuncturist, Accord Medical Clinic. MBBS (NUS), Graduate Diploma in Family Medicine (NUS), Graduate Diploma in Acupuncture (Singapore College of TCM).
Last reviewed: August 2026
This page is general health education, not medical advice. Whether any treatment is appropriate for you is a decision made in consultation after assessment.